APL Nameplate
  • Volume/Page
  • Keyword
  • DOI
  • Citation
  • Advanced
   
 
 
 

Flickr Twitter UniPHY Group iResearch App Facebook

Applied Physics Letters / Volume 96 / Issue 15 / BIOPHYSICS AND BIO-INSPIRED SYSTEMS

Appl. Phys. Lett. 96, 153702 (2010); http://dx.doi.org/10.1063/1.3383223 (3 pages)

Behavior of Caenorhabditis elegans in alternating electric field and its application to their localization and control

Pouya Rezai1, Asad Siddiqui2, Ponnambalam Ravi Selvaganapathy1, and Bhagwati P. Gupta2

1Department of Mechanical Engineering, McMaster University, Hamilton, Ontario L8S 4L7, Canada
2Department of Biology, McMaster University, Hamilton, Ontario L8S 4L7, Canada

View MapView Map

(Received 17 February 2010; accepted 11 March 2010; published online 14 April 2010)

Caenorhabditis elegans is an attractive model organism because of its genetic similarity to humans and the ease of its manipulation in the laboratory. Recently, it was shown that a direct current electric field inside microfluidic channel induces directed movement that is highly sensitive, reliable, and benign. In this letter, we describe the worm’s movement response to alternating electric fields in a similar channel setup. We demonstrate that the 1 Hz and higher frequency of alternating current field can effectively localize worms in the channel. This discovery could potentially help design microfluidic devices for high throughput automated analysis of worms.

© 2010 American Institute of Physics

RELATED DATABASES

To view database links for this article, you need to log in.

KEYWORDS and PACS

Keywords

bioelectric phenomena, biomedical equipment, bioMEMS, microfluidics, neuromuscular stimulation, zoology

PACS

  • 87.50.ct

    Therapeutic applications

  • 87.85.D-

    Applied neuroscience

  • 87.19.Ff

    Muscles

  • 87.85.Ox

    Biomedical instrumentation and transducers, including micro-electro-mechanical systems (MEMS)

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.3383223

PUBLICATION DATA

ISSN

0003-6951 (print)  
1077-3118 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.

For access to citing articles, you need to log in.


Access to article objects (figures, tables, multimedia) requires a subscription; log in to view available files.
(Access to supplementary files, where available, is free for this journal.)

Access to article objects (figures, tables, multimedia) requires a subscription; log in to view available files.
(Access to supplementary files, where available, is free for this journal.)



Close

Google Calendar

ADVERTISEMENT

Your Recent History Recent History Help

Recently Viewed

  1. Behavior of Caenorhabditis elegans in alternating electric field and its application to their localization and control
  2. Strain states in a quantum well embedded into a rolled-up microtube: X-ray and photoluminescence studies
  3. Quasicontinuous refractive index tailoring of SiNx and SiOxNy for broadband antireflective coatings
  4. High performance airbrushed organic thin film transistors
  5. AlGaAs/GaAs single electron transistor fabricated without modulation doping
Go to AIP Home
Copyright © American Institute of Physics
close