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30 Apr 2012

Volume 100, Issue 18, Articles (18xxxx)

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Appl. Phys. Lett. 100, 181901 (2012); http://dx.doi.org/10.1063/1.4705414 (4 pages)

Etienne Brasselet, Arnaud Royon, and Lionel Canioni
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Separation of blood cells using hydrodynamic lift

T. M. Geislinger, B. Eggart, S. Braunmüller, L. Schmid, and T. Franke

Appl. Phys. Lett. 100, 183701 (2012); http://dx.doi.org/10.1063/1.4709614 (4 pages) | Cited 5 times

Online Publication Date: 3 May 2012

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Using size and deformability as intrinsic biomarkers, we separate red blood cells (RBCs) from other blood components based on a repulsive hydrodynamic cell-wall-interaction. We exploit this purely viscous lift effect at low Reynolds numbers to induce a lateral migration of soft objects perpendicular to the streamlines of the fluid, which closely follows theoretical prediction by Olla [J. Phys. II 7, 1533, (1997)]. We study the effects of flow rate and fluid viscosity on the separation efficiency and demonstrate the separation of RBCs, blood platelets, and solid microspheres from each other. The method can be used for continuous and label-free cell classification and sorting in on-chip blood analysis.
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87.19.U- Hemodynamics
87.85.gf Fluid mechanics and rheology

Electron heating mode transition induced by ultra-high frequency in atmospheric microplasmas for biomedical applications

H. C. Kwon, I. H. Won, and J. K. Lee

Appl. Phys. Lett. 100, 183702 (2012); http://dx.doi.org/10.1063/1.4711207 (4 pages) | Cited 2 times

Online Publication Date: 4 May 2012

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The electron heating mode transition induced by ultra-high frequency in atmospheric-pressure microplasmas was investigated using particle-in-cell simulation with a Monte Carlo collision. Interestingly, this discharge mode transition is accompanied by non-monotonic evolution of electron kinetics such as effective electron temperature, plasma density, and electron energy on the electrode. In this study, the highest flux of energetic electrons (ɛ > 4 eV) usable for tailoring the surface chemistry in atmospheric microplasmas is obtained at the specific frequency (400 MHz), where an optimal trade-off is established between the amplitude of sheath oscillations and the power coupled to electrons for sub-millimeter dimensions (200 µm).
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52.50.Qt Plasma heating by radio-frequency fields; ICR, ICP, helicons
52.80.Pi High-frequency and RF discharges
52.25.Dg Plasma kinetic equations
52.40.Kh Plasma sheaths
52.35.Fp Electrostatic waves and oscillations (e.g., ion-acoustic waves)
52.65.Rr Particle-in-cell method
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