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30 Jan 2012

Volume 100, Issue 5, Articles (05xxxx)

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Appl. Phys. Lett. 100, 053101 (2012); http://dx.doi.org/10.1063/1.3679127 (3 pages)

Shinya Kano, Yasuyuki Yamada, Kentaro Tanaka, and Yutaka Majima
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ZnS-nanocrystals/polypyrrole nanocomposite film based immunosensor

Sujeet K. Mishra, Renu Pasricha, Ashok M Biradar, and Rajesh

Appl. Phys. Lett. 100, 053701 (2012); http://dx.doi.org/10.1063/1.3681580 (4 pages) | Cited 3 times

Online Publication Date: 1 February 2012

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We report an electrochemically synthesized ZnS nanocrystals modified polypyrrole (PPy) nanocomposite film based immunosensor for the detection of C-reactive protein (αCRP). The ZnS-PPy composite film was characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM) and electrochemical techniques. The modified film showed good biocompatibility with efficient binding to protein antibody (αCRP-Ab) molecules through ZnS nanocrystals, exhibited an attractive platform for immunosensor fabrication. The electrical and sensing properties of the polymer composite film of different thickness towards protein antigen (αCRP-Ag) were delineated. The immunosensor exhibited an impedance response to αCRP-Ag concentration in a linear range from 10 ng to 10 μg mL−1.
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87.85.Rs Nanotechnologies-applications
81.07.-b Nanoscale materials and structures: fabrication and characterization
82.35.Np Nanoparticles in polymers
82.35.Pq Biopolymers, biopolymerization
87.14.E- Proteins

Three-dimensional control of Tetrahymena pyriformis using artificial magnetotaxis

Dal Hyung Kim, Paul Seung Soo Kim, Anak Agung Julius, and Min Jun Kim

Appl. Phys. Lett. 100, 053702 (2012); http://dx.doi.org/10.1063/1.3678340 (3 pages)

Online Publication Date: 2 February 2012

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We demonstrate three-dimensional control with the eukaryotic cell Tetrahymena pyriformis (T. pyriformis) using two sets of Helmholtz coils for xy-plane motion and a single electromagnet for z-direction motion. T. pyriformis is modified to have artificial magnetotaxis with internalized magnetite. To track the cell’s z-axis position, intensity profiles of non-motile cells at varying distances from the focal plane are used. During vertical motion along the z-axis, the intensity difference is used to determine the position of the cell. The three-dimensional control of the live microorganism T. pyriformis as a cellular robot shows great potential for practical applications in microscale tasks, such as target transport and cell therapy.
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87.17.-d Cell processes
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