APL Nameplate
  • Volume/Page
  • Keyword
  • DOI
  • Citation
  • Advanced
   
 
 
 

Flickr Twitter iResearch App Facebook

BROWSE VOLUMES

Year Range: 
Search Issue | RSS Feeds RSS
Previous Issue Next Issue

17 Jul 2000

Volume 77, Issue 3, pp. 313-459

Return to All Sections
back to top
RSS Feeds

Mechanical resonant immunospecific biological detector

B. Ilic, D. Czaplewski, H. G. Craighead, P. Neuzil, C. Campagnolo, and C. Batt

Appl. Phys. Lett. 77, 450 (2000); http://dx.doi.org/10.1063/1.127006 (3 pages) | Cited 176 times

Full Text: Read Online (HTML) | Download PDF

Show Abstract
We have demonstrated high-sensitivity detection of bacteria using an array of bulk micromachined resonant cantilevers. The biological sensor is a micromechanical oscillator that consists of an array of silicon-nitride cantilevers with an immobilized antibody layer on the surface of the resonator. Measured resonant frequency shift as a function of the additional cell loading was observed and correlated to the mass of the specifically bound Escherichia coli O157:H7 cells. Deposition and subsequent detection of E. coli cells was achieved under ambient conditions. © 2000 American Institute of Physics.
Show PACS
87.85.Va Micromachining
87.85.Ng Biological signal processing
Return to All Sections
Close

Google Calendar

ADVERTISEMENT

Go to AIP Home   © AIP Publishing LLC
close