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24 Jul 2000

Volume 77, Issue 4, pp. 463-603

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Piconewton regime dynamic force microscopy in liquid

Javier Tamayo, Andrew D. L. Humphris, and Mervyn J. Miles

Appl. Phys. Lett. 77, 582 (2000); http://dx.doi.org/10.1063/1.127051 (3 pages) | Cited 65 times

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Show Abstract
In this work, a cantilever in a fluid is driven by a mixed signal composed of a standard driving signal and a feedback signal consisting of the amplified and phase shifted oscillation signal. This mimics the oscillation of a cantilever with a quality factor up to three orders of magnitude higher than its natural Q ( ∼ 1). This technique allows the identification of the resonance frequency of the cantilever by mechanical excitation of the fluid. The improved sensitivity has been checked by imaging a very soft sample of 1% agarose gel in the dynamic mode. A force smaller than 50 pN could be applied to the sample, improving the spatial resolution and the phase contrast significantly. This technique provides a major improvement in atomic force microscopy/spectroscopy in liquids. © 2000 American Institute of Physics.
Show PACS
07.79.Lh Atomic force microscopes
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