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28 Oct 2002

Volume 81, Issue 18, pp. 3311-3500

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Geometric manipulation of DNA molecules with a laser

Y. Matsuzawa, K. Hirano, A. Mizuno, M. Ichikawa, and K. Yoshikawa

Appl. Phys. Lett. 81, 3494 (2002); http://dx.doi.org/10.1063/1.1516263 (3 pages) | Cited 1 time

Online Publication Date: 22 October 2002

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The present study reports on the geometric manipulation of DNA molecules condensed by treatment with PEG and salt with laser on a microscope. To date, the majority of previously reported laser studies have dealt with the trapping or transportation of target objects. Here, we demonstrate the successful attachment and transformation of condensed DNA molecules as well as the construction of various configurations. Laser manipulation of DNA has fruitful applicability in chemistry, life science, and biotechnology. © 2002 American Institute of Physics.
Show PACS
87.14.G- Nucleic acids
87.50.W- Optical/infrared radiation effects
87.15.B- Structure of biomolecules
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