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5 Jan 2004

Volume 84, Issue 1, pp. 1-157

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Appl. Phys. Lett. 84, 151 (2004); http://dx.doi.org/10.1063/1.1637950 (3 pages)

M. Feng, N. Holonyak, and W. Hafez
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Brownian modulated optical nanoprobes

C. J. Behrend, J. N. Anker, and R. Kopelman

Appl. Phys. Lett. 84, 154 (2004); http://dx.doi.org/10.1063/1.1637963 (3 pages) | Cited 21 times

Online Publication Date: 30 December 2003

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Brownian modulated optical nanoprobes (Brownian MOONs) are fluorescent micro- and nanoparticles that resemble moons: one hemisphere emits a bright fluorescent signal, while an opaque metal darkens the other hemisphere. Brownian motion causes the particles to tumble and blink erratically as they rotate literally through the phases of the moon. The fluctuating probe signals are separated from optical and electronic backgrounds using principal components analysis or images analysis. Brownian MOONs enable microrheological measurements on size scales and timescales that are difficult to study with other methods. Local chemical concentrations can be measured simultaneously, using spectral characteristics of indicator dyes embedded within the MOONs. © 2004 American Institute of Physics.
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61.46.-w Structure of nanoscale materials
06.30.-k Measurements common to several branches of physics and astronomy
83.85.Jn Viscosity measurements
83.10.Mj Molecular dynamics, Brownian dynamics
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