APL Nameplate
  • Volume/Page
  • Keyword
  • DOI
  • Citation
  • Advanced
   
 
 
 

Flickr Twitter iResearch App Facebook

SECTION LISTING

BROWSE VOLUMES

Year Range: 
Search Issue | RSS Feeds RSS
Previous Issue

28 Jun 2004

Volume 84, Issue 26, pp. 5299-5475

Issue Cover Spotlight Figure

Appl. Phys. Lett. 84, 5398 (2004); http://dx.doi.org/10.1063/1.1767591 (3 pages)

E. Menard, K. J. Lee, D.-Y. Khang, R. G. Nuzzo, and J. A. Rogers
Enlarge Image | Read More
Return to All Sections
back to top
RSS Feeds

Cancer treatment by ultrasound: Increasing the depth of necrosis

David Melodelima and Dominique Cathignol

Appl. Phys. Lett. 84, 5365 (2004); http://dx.doi.org/10.1063/1.1767277 (3 pages) | Cited 7 times

Online Publication Date: 17 June 2004

Full Text: | Download PDF

Show Abstract
Tissue coagulation by high-intensity ultrasound is a well-established method of cancer treatment. It suffers, however, from insufficient depth of action in the case of deep-seated tumors where endoscopic or interstitial applicators are used. It is demonstrated here that this depth can be increased by temporarily creating cavitation bubbles in such a way that ultrasound attenuation becomes stronger in the zone where tissue heating is insufficient. In vitro experiments in liver tissue confirm that bubbles are indeed located in this zone and that the effective depth of coagulation necrosis is doubled.
Show PACS
87.50.yt Therapeutic applications
87.50.Y- Biological effects of acoustic and ultrasonic energy
87.19.X- Diseases
Return to All Sections
Close

Google Calendar

ADVERTISEMENT

Go to AIP Home   © AIP Publishing LLC
close