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Applied Physics Letters / Volume 85 / Issue 16 / APPLIED BIOPHYSICS

Appl. Phys. Lett. 85, 3626 (2004); http://dx.doi.org/10.1063/1.1808885 (3 pages)

Fabrication and characterization of a biologically sensitive field-effect transistor using a nanocrystalline diamond thin film

Wensha Yang and Robert J. Hamers

Department of Chemistry, University of Wisconsin—Madison, 1101 University Avenue, Madison, Wisconsin 53706

(Received 17 June 2004; accepted 24 August 2004)

We report the fabrication and characterization of a biologically sensitive field-effect transistor (Bio-FET) using a nanocrystalline diamond thin film. Biomolecular recognition capability was provided by linking human immunoglobulin G (IgG) to the diamond surface. Electrical measurements reveal behavior characteristic of field-effect transistors. The biomolecular recognition and specificity characteristics were tested using the two antibodies anti IgM and anti-IgG. Electrical measurements show that the Bio-FET device made on an IgG-modified diamond exhibits a response specific to the anti-IgG antibody. Our results demonstrate the ability to fabricate a bio-FET device using a biologically modified diamond thin film.

© 2004 American Institute of Physics

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KEYWORDS and PACS

Keywords

diamond, organic compounds, elemental semiconductors, nanostructured materials, semiconductor thin films, field effect transistors, plasma CVD, biomolecular electronics, molecular biophysics

PACS

  • 81.05.Cy

    Elemental semiconductors

  • 81.07.Bc

    Nanocrystalline materials

  • 85.30.Tv

    Field effect devices

  • 85.65.+h

    Molecular electronic devices

  • 73.61.Cw

    Elemental semiconductors

  • 73.61.Ph

    Polymers; organic compounds

  • 61.46.-w

    Structure of nanoscale materials

  • 68.55.A-

    Nucleation and growth

  • 68.55.-a

    Thin film structure and morphology

  • 81.15.Gh

    Chemical vapor deposition (including plasma-enhanced CVD, MOCVD, ALD, etc.)

  • 87.15.-v

    Biomolecules: structure and physical properties

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.1808885

PUBLICATION DATA

ISSN

0003-6951 (print)  
1077-3118 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
    J. Philip, P. Hess, T. Feygelson, J. E. Butler, S. Chattopadhyay, K. H. Chen, and L. C. Chen, J. Appl. Phys. 93, 2164 (2003)JAPIAU000093000004002164000001.


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