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2 Aug 2004

Volume 85, Issue 5, pp. 701-848

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Appl. Phys. Lett. 85, 807 (2004); http://dx.doi.org/10.1063/1.1777817 (3 pages)

Henry J. Liu and Kyeongjae Cho
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Real-time three-dimensional optoacoustic imaging using an acoustic lens system

J. J. Niederhauser, M. Jaeger, and M. Frenz

Appl. Phys. Lett. 85, 846 (2004); http://dx.doi.org/10.1063/1.1777820 (3 pages) | Cited 25 times

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Show Abstract
In medical optoacoustics (photoacoustics), absorbing structures, such as blood vessels, hidden inside scattering media are illuminated with short laser pulses resulting in the generation of thermoelastic pressure transients. This initial three-dimensional (3D) acoustic pressure distribution, which exactly resembles the absorption distribution, was imaged into a water container with a 4f acoustic lens system. An optical dark-field stereo imaging system using a 30 ns flash illumination light was used to capture a snapshot of the pressure-induced refraction index changes in the water container at a predetermined time after the original laser pulse. The imaging system works at 20 Hz frame rate and was designed toward a theoretical resolution of 50 μm. The proposed method directly provides 3D images of absorbing structures without the need of computational reconstruction algorithms.
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87.63.Hg Thermography
43.80.Qf Medical diagnosis with acoustics
43.35.Ud Thermoacoustics, high temperature acoustics, photoacoustic effect
43.58.-e Acoustical measurements and instrumentation
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