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12 Sep 2005

Volume 87, Issue 11, Articles (11xxxx)

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Appl. Phys. Lett. 87, 113902 (2005); http://dx.doi.org/10.1063/1.2045549 (3 pages)

M. Laroussi and X. Lu
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Dielectric properties of biological molecules in the Terahertz gap

Ramakrishnan Parthasarathy, Tatiana Globus, Tatyana Khromova, Nathan Swami, and Dwight Woolard

Appl. Phys. Lett. 87, 113901 (2005); http://dx.doi.org/10.1063/1.2046730 (3 pages) | Cited 15 times

Online Publication Date: 8 September 2005

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In this work, results from parallel measurements of reflection and transmission spectra of biological molecules were utilized to enable detailed and direct calculation of the refractive index and absorption coefficient spectra in the Terahertz gap. The DNA samples from herring and salmon, as well as the protein Ovalbumin sample, have been characterized. The modeling technique is described. The reflection spectra have resonance features similar to those demonstrated earlier for transmission, thereby reaffirming molecular vibrational modes in biological materials. The dispersion of refractive index and absorption coefficient is demonstrated within the Terahertz gap of 10 cm−1 to 25 cm−1. The data yielded higher refractive index and absorption coefficient for the single stranded salmon DNA than for the double stranded counterpart, with several different vibrational modes.
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87.15.M- Spectra of biomolecules
87.14.G- Nucleic acids
87.14.E- Proteins
36.20.Ng Vibrational and rotational structure, infrared and Raman spectra
33.20.Bx Radio-frequency and microwave spectra
33.20.Tp Vibrational analysis

Room-temperature atmospheric pressure plasma plume for biomedical applications

M. Laroussi and X. Lu

Appl. Phys. Lett. 87, 113902 (2005); http://dx.doi.org/10.1063/1.2045549 (3 pages) | Cited 176 times

Online Publication Date: 8 September 2005

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As low-temperature nonequilibrium plasmas come to play an increasing role in biomedical applications, reliable and user-friendly sources need to be developed. These plasma sources have to meet stringent requirements such as low temperature (at or near room temperature), no risk of arcing, operation at atmospheric pressure, preferably hand-held operation, low concentration of ozone generation, etc. In this letter, we present a device that meets exactly such requirements. This device is capable of generating a cold plasma plume several centimeters in length. It exhibits low power requirements as shown by its current-voltage characteristics. Using helium as a carrier gas, very little ozone is generated and the gas temperature, as measured by emission spectroscopy, remains at room temperature even after hours of operations. The plasma plume can be touched by bare hands and can be directed manually by a user to come in contact with delicate objects and materials including skin and dental gum without causing any heating or painful sensation.
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87.80.-y Biophysical techniques (research methods)
52.77.-j Plasma applications
52.75.-d Plasma devices
52.50.Dg Plasma sources
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