APL Nameplate
  • Volume/Page
  • Keyword
  • DOI
  • Citation
  • Advanced
   
 
 
 

Flickr Twitter iResearch App Facebook

BROWSE VOLUMES

Year Range: 
Search Issue | RSS Feeds RSS
Previous Issue Next Issue

30 Jan 2006

Volume 88, Issue 5, Articles (05xxxx)

Issue Cover Spotlight Figure

Appl. Phys. Lett. 88, 051101 (2006); http://dx.doi.org/10.1063/1.2168491 (3 pages)

H. Lohmeyer, K. Sebald, C. Kruse, R. Kröger, J. Gutowski, D. Hommel, J. Wiersig, N. Baer, and F. Jahnke
Enlarge Image | Read More
Return to All Sections
back to top
RSS Feeds

Integrated structural and functional optical imaging combining spectral-domain optical coherence and multiphoton microscopy

Claudio Vinegoni, Tyler Ralston, Wei Tan, Wei Luo, Daniel L. Marks, and Stephen A. Boppart

Appl. Phys. Lett. 88, 053901 (2006); http://dx.doi.org/10.1063/1.2171477 (3 pages) | Cited 31 times

Online Publication Date: 31 January 2006

Full Text: Read Online (HTML) | Download PDF

Show Abstract
An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multiphoton microscopy for the detection of two-photon fluorescence and second harmonic generation signals. The unique configuration of this integrated microscope allows for the simultaneous acquisition of both anatomical (structural) and functional imaging information with particular emphasis for applications in the fields of tissue engineering and cell biology. In addition, the contemporary analysis of the spectroscopic features can enhance contrast by differentiating among different tissue components.
Show PACS
87.63.L- Visual imaging
87.85.Lf Tissue engineering
87.17.-d Cell processes
87.64.M- Optical microscopy
87.64.mn Multiphoton

Polymeric microlenses for real-time aqueous and nonaqueous organic imaging

Chao-Min Cheng, James D. Kubicek, and Philip R. LeDuc

Appl. Phys. Lett. 88, 053902 (2006); http://dx.doi.org/10.1063/1.2170136 (3 pages) | Cited 5 times

Online Publication Date: 1 February 2006

Full Text: Read Online (HTML) | Download PDF

Show Abstract
A simple and efficient polydimethylsiloxane microlens is made through controlling surface interactions, which can be integrated into soft lithographic systems. Lenses are created by controlling the solid-liquid interface between a droplet of liquid polydimethylsiloxane and a polymer substrate. By altering the surface characteristics, we control the contact angles of the droplet, which creates defined diameters and magnifications of these lenses. Furthermore, we demonstrate the ability to integrate these devices into culture systems enabling real-time magnified biological imaging in both aqueous and nonaqueous environments. This method has potential applications in fields including functional biomimetic microlenses, optical trapping, and endoscopy.
Show PACS
87.63.L- Visual imaging
87.80.Cc Optical trapping
42.79.Bh Lenses, prisms and mirrors
42.70.Jk Polymers and organics
37.10.Vz Mechanical effects of light on atoms, molecules, and ions
Return to All Sections
Close

Google Calendar

ADVERTISEMENT

Go to AIP Home   © AIP Publishing LLC
close