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14 Aug 2006

Volume 89, Issue 7, Articles (07xxxx)

Issue Cover Spotlight Figure

Appl. Phys. Lett. 89, 073501 (2006); http://dx.doi.org/10.1063/1.2335838 (3 pages)

Ingrid Graz, Martin Kaltenbrunner, Christoph Keplinger, Reinhard Schwödiauer, Siegfried Bauer, Stéphanie P. Lacour, and Sigurd Wagner
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Swept laser source at 1 μm for Fourier domain optical coherence tomography

Jun Zhang, Qiang Wang, Bin Rao, Zhongping Chen, and Kevin Hsu

Appl. Phys. Lett. 89, 073901 (2006); http://dx.doi.org/10.1063/1.2335405 (3 pages) | Cited 9 times

Online Publication Date: 16 August 2006

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A frequency swept source at 1 μm wavelength for Fourier domain optical coherence tomography (FDOCT) was demonstrated. The source incorporates a fiber-coupled semiconductor optical amplifier gain module, a fiber Fabry-Pérot tunable filter, and fiber isolators to form a ring laser. The laser is capable of a scanning range of 64 nm, 3 dB sweep range of 31 nm, and coherence length of 9.8 mm at 2 kHz sweep rate. Based on the swept source, a FDOCT system was developed which can achieve 12 μm axial resolution in tissue. Imaging of pig retina was demonstrated with the FDOCT system.
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87.63.L- Visual imaging
42.62.Be Biological and medical applications
42.55.Wd Fiber lasers
42.60.By Design of specific laser systems
42.55.Px Semiconductor lasers; laser diodes
42.60.Da Resonators, cavities, amplifiers, arrays, and rings

Sterilization mechanism for Escherichia coli by plasma flow at atmospheric pressure

Takehiko Sato, Takashi Miyahara, Akiko Doi, Shiroh Ochiai, Takuya Urayama, and Tatsuyuki Nakatani

Appl. Phys. Lett. 89, 073902 (2006); http://dx.doi.org/10.1063/1.2336594 (2 pages) | Cited 33 times

Online Publication Date: 18 August 2006

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A mechanism for sterilizing Escherichia coli by a flowing postdischarge and UV radiation of argon plasma at atmospheric pressure was investigated by analyzing the surviving cells and the potassium leakage of cytoplasmic material and by morphological observation. Inactivation of E. coli results from the destruction of the cytoplasmic membrane and the outer membrane under plasma exposure and the destruction of nucleic acids by exposure to ultraviolet radiation from the plasma source.
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87.80.-y Biophysical techniques (research methods)
87.53.-j Effects of ionizing radiation on biological systems
87.16.D- Membranes, bilayers, and vesicles
87.14.G- Nucleic acids
52.77.-j Plasma applications
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