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21 Aug 2006

Volume 89, Issue 8, Articles (08xxxx)

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Appl. Phys. Lett. 89, 074103 (2006); http://dx.doi.org/10.1063/1.2337528 (2 pages)

J. M. Yi, J. H. Je, Y. S. Chu, Y. Zhong, Y. Hwu, and G. Margaritondo
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Selective surface treatment of micro printing pin and its performance

Jane Gin Fai Tsai, Zugen Chen, Stanley F. Nelson, and Chang-Jin Kim

Appl. Phys. Lett. 89, 083901 (2006); http://dx.doi.org/10.1063/1.2337882 (3 pages)

Online Publication Date: 22 August 2006

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Biological microarray construction relies on the sequential deposition of liquid samples, typically by contact or ink-jet printing. One drawback of contact printing is excessive solution pickup on the pin’s outer surface, resulting in inefficiency. The authors combated this problem with a simple method that treats pin surfaces selectively so the outer surface becomes hydrophobic while the inner surface remains hydrophilic. Silicon-micromachined pins were utilized to evaluate the effect. The results demonstrated elimination of preprinting, greater droplet size consistency (e.g., 42±5 μm vs 63±13 μm), and more spots ( ∼ 800 vs ∼ 300) printed per loading. Consequently, an average spot diameter, between 30 and 100 μm, can be controlled, depending on the pin design.
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87.80.-y Biophysical techniques (research methods)
85.85.+j Micro- and nano-electromechanical systems (MEMS/NEMS) and devices
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