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Applied Physics Letters / Volume 93 / Issue 11 / LASERS, OPTICS, AND OPTOELECTRONICS

Appl. Phys. Lett. 93, 111113 (2008); http://dx.doi.org/10.1063/1.2987484 (3 pages)

Plastic distributed feedback laser biosensor

M. Lu, S. S. Choi, U. Irfan, and B. T. Cunningham

Department of Electrical and Computer Engineering, Micro and Nanotechnology Laboratory, University of Illinois, Urbana, Illinois 61801, USA

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(Received 30 July 2008; accepted 28 August 2008; published online 18 September 2008)

A replica-molded plastic-based vertically emitting distributed feedback (DFB) laser has been demonstrated for label-free chemical and biomolecular detection in which the emission wavelength is modulated by changes in bulk and surface-adsorbed material permittivity. A one-dimensional surface grating formed in UV-curable polymer on a flexible plastic substrate is coated with a thin polymer film incorporating organic laser dye. When optically pumped with a ∼ 10 ns pulse at λ = 532 nm, the DFB laser exhibits stimulated emission in the λ = 585–620 nm wavelength range with a linewidth as narrow as δλ = 0.09 nm. While exposed to chemical solutions with different refractive indices and adsorbed charged polymer monolayers, the laser sensor demonstrates single mode emission over a tuning range of ∼ 14 nm and the ability to perform kinetic monitoring of surface-adsorbed mass. A protein-protein interaction experiment is used to demonstrate the capability to characterize antibody-antigen affinity binding constants.

© 2008 American Institute of Physics

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KEYWORDS and PACS

Keywords

biochemistry, biological techniques, distributed feedback lasers, dye lasers, molecular biophysics, optical sensors, permittivity, polymer films, proteins

PACS

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.2987484

PUBLICATION DATA

ISSN

0003-6951 (print)  
1077-3118 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
    N. M. Hanumegowda, C. J. Stica, B. C. Patel, I. White, and X. D. Fan, Appl. Phys. Lett. 87, 201107 (2005)APPLAB000087000020201107000001.

    F. Vollmer, D. Braun, A. Libchaber, M. Khoshsima, I. Teraoka, and S. Arnold, Appl. Phys. Lett. 80, 4057 (2002)APPLAB000080000021004057000001.

    M. Lu, S. Choi, C. J. Wagner, J. G. Eden, and B. T. Cunningham, Appl. Phys. Lett. 92, 261502 (2008)APPLAB000092000026261502000001.

    W. Fang, D. B. Buchholz, R. C. Bailey, J. T. Hupp, R. P. H. Chang, and H. Cao, Appl. Phys. Lett. 85, 3666 (2004)APPLAB000085000017003666000001.

    M. Loncar, A. Scherer, and Y. M. Qiu, Appl. Phys. Lett. 82, 4648 (2003)APPLAB000082000026004648000001.

    J. A. Rogers, M. Meier, A. Dodabalapur, E. J. Laskowski, and M. A. Cappuzzo, Appl. Phys. Lett. 74, 3257 (1999)APPLAB000074000022003257000001.


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