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10 Nov 2008

Volume 93, Issue 19, Articles (19xxxx)

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Appl. Phys. Lett. 93, 192501 (2008); http://dx.doi.org/10.1063/1.3013857 (3 pages)

O. Hellwig, A. Moser, E. Dobisz, Z. Z. Bandic, H. Yang, D. S. Kercher, J. D. Risner-Jamtgaard, D. Yaney, and E. E. Fullerton
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A liquid waveguide based evanescent wave sensor integrated onto a microfluidic chip

X. C. Li, J. Wu, A. Q. Liu, Z. G. Li, Y. C. Soew, H. J. Huang, K. Xu, and J. T. Lin

Appl. Phys. Lett. 93, 193901 (2008); http://dx.doi.org/10.1063/1.2988648 (3 pages) | Cited 16 times

Online Publication Date: 12 November 2008

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An evanescent wave sensor based on liquid waveguide is integrated onto a microfluidic chip. The structure of the liquid waveguide consists of three streams with two low refractive index fluids as cladding layers, which envelop a high refractive index fluid as a core layer along a microchannel. Light is coupled into the core layer, and a detected sample is injected into one cladding layer. The profile of the output light modal power is changed by varying the concentration of the sample. The sensor with a sensitivity of 275 μm2 l/mol can be used for real-time, low-cost, and label-free measurements in a wide range of applications.
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42.81.Pa Sensors, gyros
42.79.Gn Optical waveguides and couplers
47.85.Np Fluidics
85.85.+j Micro- and nano-electromechanical systems (MEMS/NEMS) and devices

A mean field approach to many-particles effects in dielectrophoresis

O. E. Nicotra, A. La Magna, and S. Coffa

Appl. Phys. Lett. 93, 193902 (2008); http://dx.doi.org/10.1063/1.3025840 (3 pages) | Cited 3 times

Online Publication Date: 13 November 2008

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One of the major applications of the dielectrophoresis is selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particles effects due to high concentration of biological material around electrodes can cause a rapid decrease in trapping efficiency in dielectrophoretic devices. In this paper we present an approach based on a drift-diffusion dynamics to study the particles behavior near electrodes surroundings. Within this approach, we introduce many-particles effects by invoking the effective medium approximation, electrodes can saturate losing their capability to attract further particles and thus leading to a more realistic scenario never shown in past literature.
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82.45.Fk Electrodes
87.80.Kc Electrochemical techniques

Chirality of sulforhodamine dye molecules incorporated in DNA thin films

A. J. Steckl, H. Spaeth, K. Singh, J. Grote, and R. Naik

Appl. Phys. Lett. 93, 193903 (2008); http://dx.doi.org/10.1063/1.3027070 (3 pages) | Cited 4 times

Online Publication Date: 13 November 2008

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Thin films formed from salmon sperm DNA reacted with a cationic surfactant (CTMA-Cl) included up to 25 wt % fluorescent molecule sulforhodamine (SRh). SRh effect on DNA chirality and vice versa was investigated by circular dichroism (CD) spectroscopy. The CD signals at 250–265 nm indicate that DNA chirality was maintained or enhanced. Induced CD (iCD) signal at 580–610 nm indicates that SRh is chiral in DNA/CTMA. iCD signal from both solutions and thin films generally increases with SRh concentration. The chirality induced in SRh molecules and the absence of significant DNA reduction in chirality are clear indicators of strong binding to DNA/CTMA.
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87.14.gk DNA
87.15.R- Reactions and kinetics
33.15.Bh General molecular conformation and symmetry; stereochemistry
36.20.Ey Conformation (statistics and dynamics)
33.55.+b Optical activity and dichroism
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