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5 Jan 2009

Volume 94, Issue 1, Articles (01xxxx)

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Appl. Phys. Lett. 94, 013102 (2009); http://dx.doi.org/10.1063/1.3062938 (3 pages)

Hao-Chih Yuan, Jonghyun Shin, Guoxuan Qin, Lei Sun, Pallab Bhattacharya, Max G. Lagally, George K. Celler, and Zhenqiang Ma
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Thermal vapor bubble and pressure dynamics during infrared laser ablation of tissue

Wolfgang Wagner, Adam Sokolow, Robert Pearlstein, and Glenn Edwards

Appl. Phys. Lett. 94, 013901 (2009); http://dx.doi.org/10.1063/1.3063127 (3 pages) | Cited 5 times

Online Publication Date: 6 January 2009

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Free-electron laser irradiation can superheat tissue water, driving thermal vapor bubbles confined by tissue matrix and leading to mechanical tissue failure (ablation). Acoustic transients propagating from an ablation cavity were recorded with a polarization quadrature, interferometric vibrometer. For 3.0 μm infrared irradiation, the shocklike transients with peak pressures in the megapascal range indicate amplification due to bubble collapse. In contrast, for 6.45 μm irradiation, elastic transients with peak pressures in the 0.1 MPa range indicate tissue failure during bubble growth.
Show PACS
87.50.wp Therapeutic applications
87.19.R- Mechanical and electrical properties of tissues and organs
87.50.wf Biophysical mechanisms of interaction
87.19.Pp Biothermics and thermal processes in biology
42.62.Be Biological and medical applications
87.50.yg Biophysical mechanisms of interaction
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