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28 Sep 2009

Volume 95, Issue 13, Articles (13xxxx)

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Appl. Phys. Lett. 95, 131107 (2009); http://dx.doi.org/10.1063/1.3236752 (3 pages)

Marcus Eichfelder, Wolfgang-Michael Schulz, Matthias Reischle, Michael Wiesner, Robert Roßbach, Michael Jetter, and Peter Michler
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Silicon electronics on silk as a path to bioresorbable, implantable devices

Dae-Hyeong Kim, Yun-Soung Kim, Jason Amsden, Bruce Panilaitis, David L. Kaplan, Fiorenzo G. Omenetto, Mitchell R. Zakin, and John A. Rogers

Appl. Phys. Lett. 95, 133701 (2009); http://dx.doi.org/10.1063/1.3238552 (3 pages) | Cited 38 times

Online Publication Date: 29 September 2009

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Many existing and envisioned classes of implantable biomedical devices require high performance electronics/sensors. An approach that avoids some of the longer term challenges in biocompatibility involves a construction in which some parts or all of the system resorbs in the body over time. This paper describes strategies for integrating single crystalline silicon electronics, where the silicon is in the form of nanomembranes, onto water soluble and biocompatible silk substrates. Electrical, bending, water dissolution, and animal toxicity studies suggest that this approach might provide many opportunities for future biomedical devices and clinical applications.
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87.85.fk Biosensors
87.85.J- Biomaterials

Electrostatic self-aligned placement of single nanodots by protein supramolecules

Shigeo Yoshii, Shinya Kumagai, Kazuaki Nishio, Ayako Kadotani, and Ichiro Yamashita

Appl. Phys. Lett. 95, 133702 (2009); http://dx.doi.org/10.1063/1.3236524 (3 pages) | Cited 13 times

Online Publication Date: 1 October 2009

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Electrostatic self-aligned positioning of a single 7 nm nanoparticle in the cage-shaped protein ferritin onto an aminosilane disk pattern as large as next-generation photolithography can produce is demonstrated. Genetic modification of the ferritin increased its surface charge density and therefore improved its electrostatic interaction. Single molecules of the recombinant ferritin could achieve self-aligned placement on 32–45 nm disks under the optimal solution condition, which was calculated by numerical analysis. This biological self-aligned placement, incorporated into next-generation photolithography techniques, will be a useful wafer-scale nanofabrication tool.
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87.14.E- Proteins
87.80.-y Biophysical techniques (research methods)
87.15.Pc Electronic and electrical properties

Improved contrast radially polarized coherent anti-Stokes Raman scattering microscopy using annular aperture detection

Jian Lin, Fake Lu, Haifeng Wang, Wei Zheng, Colin JR Sheppard, and Zhiwei Huang

Appl. Phys. Lett. 95, 133703 (2009); http://dx.doi.org/10.1063/1.3240874 (3 pages) | Cited 6 times

Online Publication Date: 1 October 2009

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We propose a unique annular aperture detection scheme in radially polarized coherent anti-Stokes Raman scattering (RP-CARS) microscopy for significantly removing nonresonant background for high contrast vibrational imaging. Our finite-difference time-domain calculations show that the maximum radiation patterns of RP-CARS signals from the scatterers vary with the scatterer’s sizes, which are different from nonresonant CARS radiation from surrounding water. By applying appropriate sizes of annular stop apertures in the detection path, the nonresonant background from water can be effectively suppressed, yielding over 110-fold improvements in signal-to-background ratio for the forward-detected RP-CARS, while over 50-fold improvements for the backward RP-CARS detection.
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07.60.Pb Conventional optical microscopes
42.65.Dr Stimulated Raman scattering; CARS
42.65.Es Stimulated Brillouin and Rayleigh scattering
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