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13 Jul 2009

Volume 95, Issue 2, Articles (02xxxx)

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Appl. Phys. Lett. 95, 023701 (2009); http://dx.doi.org/10.1063/1.3173808 (3 pages)

G. Devès, S. Roudeau, A. Carmona, S. Lavielle, K. Gionnet, G. Déléris, and R. Ortega
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Fluorine microimaging and quantification using nuclear reaction analysis: A tool for validating tissue distribution of positron emission tomography tracers

G. Devès, S. Roudeau, A. Carmona, S. Lavielle, K. Gionnet, G. Déléris, and R. Ortega

Appl. Phys. Lett. 95, 023701 (2009); http://dx.doi.org/10.1063/1.3173808 (3 pages)

Online Publication Date: 13 July 2009

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An application of ion beam microprobe analysis has been developed for the quantitative imaging of fluorine compounds in biological samples on a micrometer scale. The difficulty of imaging fluorine at trace level concentration in biological tissues has been addressed by using a combination of nuclear reaction analysis and proton resonant backscattering spectrometry. With this method, the limit of detection of fluorine in thin biological samples can be as low as 3 μg/g. Quantitative imaging of fluorodeoxyglucose distribution, the most widely used tracer for detection of solid tumors by positron emission tomography, is shown as an example of this application.
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87.57.uk Positron emission tomography (PET)

Dual hierarchical biomimic superhydrophobic surface with three energy states

Ming-Hung Chen, Tsung-Hsing Hsu, Yun-Ju Chuang, and Fan-Gang Tseng

Appl. Phys. Lett. 95, 023702 (2009); http://dx.doi.org/10.1063/1.3180114 (3 pages) | Cited 8 times

Online Publication Date: 17 July 2009

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A low hysteresis surface prepared by two-length-scaled hierarchical textures to mimic the Lotus effect is proposed. The fabricated textures incorporate self-masked nanorods on microextrusions. A high static contact angle (160°) and low hysteresis ( ∼ 2.7°) are obtained and comparable to the surface properties of a natural lotus leaf. The stability of hydrophobicity is described with respect to three energy states (nonwetting, microwetting, and nanowetting) based on dynamic contact angle analysis by droplet impinging onto the surface. The estimated texture-induced energy barrier based on the principle of energy conservation is in good agreement to those estimated from Laplace’s law.
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68.03.Cd Surface tension and related phenomena
68.08.Bc Wetting

Functionalized zinc oxide nanorod with ionophore-membrane coating as an intracellular Ca2+ selective sensor

M. H. Asif, A. Fulati, O. Nur, M. Willander, Cecilia Brännmark, Peter Strålfors, Sara I. Börjesson, and Fredrik Elinder

Appl. Phys. Lett. 95, 023703 (2009); http://dx.doi.org/10.1063/1.3176441 (3 pages) | Cited 6 times

Online Publication Date: 17 July 2009

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The tip of a borosilicate glass capillary with functionalized hexagonal ZnO nanorods was used to make a sensitive electrochemical intracellular Ca2+ sensor. To adjust the sensor for Ca2+ measurements with sufficient selectivity and stability, polyvinylchloride membrane containing Ca2+ ionophores were coated on the surface. The membrane covered ZnO nanorods exhibited a Ca2+-dependent electrochemical potential difference versus an Ag/AgCl reference electrode. The potential difference was linear over a large concentration range (100 nM–10 mM). The measurements of Ca2+ concentrations using our ZnO nanorods sensor in human fat cells or in frog egg cells were consistent with values of Ca2+ concentrations reported in the literature. This nanoelectrode device paves the way to measurements of intracellular biochemical species in specific locations within single living cells.
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87.85.Rs Nanotechnologies-applications
82.47.Rs Electrochemical sensors
87.80.Kc Electrochemical techniques
82.45.Fk Electrodes
85.35.-p Nanoelectronic devices
87.16.D- Membranes, bilayers, and vesicles
87.18.-h Biological complexity
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