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5 Apr 2010

Volume 96, Issue 14, Articles (14xxxx)

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Appl. Phys. Lett. 96, 143103 (2010); http://dx.doi.org/10.1063/1.3378684 (3 pages)

Joshua A. Kellar, Justice M. P. Alaboson, Qing Hua Wang, and Mark C. Hersam
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The hairline plasma: An intermittent negative dc-corona discharge at atmospheric pressure for plasma medical applications

R. Bussiahn, R. Brandenburg, T. Gerling, E. Kindel, H. Lange, N. Lembke, K.-D. Weltmann, Th. von Woedtke, and T. Kocher

Appl. Phys. Lett. 96, 143701 (2010); http://dx.doi.org/10.1063/1.3380811 (3 pages) | Cited 10 times

Online Publication Date: 6 April 2010

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A cold atmospheric pressure plasma source, called hairline plasma, for biological and medical applications has been developed. Using the physical effect of the negative dc corona discharge, a nanosecond pulsed microplasma has been created. The device produces a very thin (d ∼ 30 μm) plasma filament with a length of up to 1.5 cm. Due to this geometrical parameters this plasma is particularly suitable for the treatment of microscopic cavities. The low plasma temperature allows to treat the human skin without any heating or painful irritation.
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52.80.Hc Glow; corona
52.50.Dg Plasma sources
52.25.-b Plasma properties
52.77.-j Plasma applications

Dynamics of acoustic droplet vaporization in gas embolotherapy

Adnan Qamar, Zheng Z. Wong, J. Brian Fowlkes, and Joseph L. Bull

Appl. Phys. Lett. 96, 143702 (2010); http://dx.doi.org/10.1063/1.3376763 (3 pages) | Cited 4 times

Online Publication Date: 7 April 2010

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Acoustic droplet vaporization is investigated in a theoretical model. This work is motivated by gas embolotherapy, a developmental cancer treatment involving tumor infarction with gas microbubbles that are selectively formed from liquid droplets. The results indicate that there exists a threshold value for initial droplet size below which the bubble evolution is oscillatory and above which it is smooth and asymptotic, and show that the vaporization process affects the subsequent microbubble expansion. Dampening of the bubble expansion is observed for higher viscosity and surface tension, with effects more pronounced for droplet size less than 6 μm in radius.
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87.50.yt Therapeutic applications
87.19.U- Hemodynamics
87.50.Y- Biological effects of acoustic and ultrasonic energy
87.50.yg Biophysical mechanisms of interaction
47.85.Np Fluidics
87.80.Ek Mechanical and micromechanical techniques
87.85.-d Biomedical engineering
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