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19 Apr 2010

Volume 96, Issue 16, Articles (16xxxx)

Issue Cover Spotlight Figure

Appl. Phys. Lett. 96, 163101 (2010); http://dx.doi.org/10.1063/1.3327831 (3 pages)

Ramesh Nath, Seungbum Hong, Jeffrey A. Klug, Alexandra Imre, Michael J. Bedzyk, Ram S. Katiyar, and Orlando Auciello
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Localized Joule heating produced by ion current focusing through micron-size holes

V. Viasnoff, U. Bockelmann, A. Meller, H. Isambert, L. Laufer, and Y. Tsori

Appl. Phys. Lett. 96, 163701 (2010); http://dx.doi.org/10.1063/1.3399315 (3 pages)

Online Publication Date: 19 April 2010

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We provide an experimental demonstration that the focusing of ionic currents in a micron size hole connecting two chambers can produce local temperature increases of up to 100 °C with gradients as large as 1°K μm−1. We find a good agreement between the measured temperature profiles and a finite elements-based numerical calculation. We show how the thermal gradients can be used to measure the full melting profile of DNA duplexes within a region of 40 μm. The possibility to produce even larger gradients using submicron pores is discussed.
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87.14.gk DNA

Distributed feedback laser biosensor incorporating a titanium dioxide nanorod surface

Chun Ge, Meng Lu, Wei Zhang, and Brian T. Cunningham

Appl. Phys. Lett. 96, 163702 (2010); http://dx.doi.org/10.1063/1.3394259 (3 pages) | Cited 9 times

Online Publication Date: 19 April 2010

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A dielectric nanorod structure is used to enhance the label-free detection sensitivity of a vertically-emitting distributed feedback laser biosensor (DFBLB). The device is comprised of a replica molded plastic grating that is subsequently coated with a dye-doped polymer layer and a TiO2 nanorod layer produced by the glancing angle deposition technique. The DFBLB emission wavelength is modulated by the adsorption of biomolecules, whose greater dielectric permittivity with respect to the surrounding liquid media will increase the laser wavelength in proportion to the density of surface-adsorbed biomaterial. The nanorod layer provides greater surface area than a solid dielectric thin film, resulting in the ability to incorporate a greater number of molecules. The detection of a monolayer of protein polymer poly (Lys, Phe) is used to demonstrate that a 90 nm TiO2 nanorod structure improves the detection sensitivity by a factor of 6.6 compared to an identical sensor with a nonporous TiO2 surface.
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07.07.Df Sensors (chemical, optical, electrical, movement, gas, etc.); remote sensing
42.79.Pw Imaging detectors and sensors
87.85.fk Biosensors
07.10.Cm Micromechanical devices and systems
81.07.Bc Nanocrystalline materials

Biologically inspired porous cooling membrane using arrayed-droplets evaporation

T. Kokalj, H. Cho, M. Jenko, and L. P. Lee

Appl. Phys. Lett. 96, 163703 (2010); http://dx.doi.org/10.1063/1.3332398 (3 pages)

Online Publication Date: 21 April 2010

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Inspired by human skin that dissipates heat via sweat-droplet evaporation on the skin, we propose an evaporative cooling technique via arrayed-droplets on a porous membrane, construct an analytical model of the evaporative cooling including interactions among the large number of droplets, and extensively analyze the cooling performance of 1000-droplet array. Our model shows that heat dissipation is enhanced by the membrane with dense droplets (i.e., enhancement factor of 10 at 5000 pores/cm2 and pore radius of 35 μm with respect to human skin). Additionally, the model predicts that the membrane dissipates heat more efficiently by operating at a higher temperature (i.e., additional enhancement factor of 17 at droplet temperature of 100 °C).
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47.27.te Turbulent convective heat transfer
82.39.Wj Ion exchange, dialysis, osmosis, electro-osmosis, membrane processes
47.56.+r Flows through porous media
47.55.D- Drops and bubbles
47.63.-b Biological fluid dynamics

Analysis of connectivity map: Control to glutamate injured and phenobarbital treated neuronal network

Hassan Kamal, Rajan Kanhirodan, Kalyan V. Srinivas, and Sujit K. Sikdar

Appl. Phys. Lett. 96, 163704 (2010); http://dx.doi.org/10.1063/1.3398025 (3 pages) | Cited 1 time

Online Publication Date: 21 April 2010

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We study the responses of a cultured neural network when it is exposed to epileptogenesis glutamate injury causing epilepsy and subsequent treatment with phenobarbital by constructing connectivity map of neurons using correlation matrix. This study is particularly useful in understanding the pharmaceutical drug induced changes in the neuronal network properties with insights into changes at the systems biology level.
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87.19.lj Neuronal network dynamics
87.18.Sn Neural networks and synaptic communication
87.85.dq Neural networks
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