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4 Jan 2010

Volume 96, Issue 1, Articles (01xxxx)

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Appl. Phys. Lett. 96, 013107 (2010); http://dx.doi.org/10.1063/1.3280900 (3 pages)

L. Fernández, M. Corso, F. Schiller, M. Ilyn, M. Holder, and J. E. Ortega
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Detection of an endocrine disrupter biomarker, vitellogenin, in largemouth bass serum using AlGaN/GaN high electron mobility transistors

Byung Hwan Chu, C. Y. Chang, Kevin Kroll, Nancy Denslow, Yu-Lin Wang, S. J. Pearton, A. M. Dabiran, A. M. Wowchak, B. Cui, P. P. Chow, and Fan Ren

Appl. Phys. Lett. 96, 013701 (2010); http://dx.doi.org/10.1063/1.3279159 (3 pages) | Cited 3 times

Online Publication Date: 5 January 2010

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Endocrine disrupters are known to have negative effects on the environment and human health. Real time detection of vitellogenin, an endocrine disrupter biomarker, was demonstrated using AlGaN/GaN high electron mobility transistors (HEMTs). Anti-vitellogenin antibodies were chemically anchored to the gold-coated gate area of the HEMT and immobilized with thioglycolic acid. The potential difference that occurs from the vitellogenin antigen-antibody interaction-induced caused a drain current change in the HEMT. The HEMT sensor was tested for vitellogenin detection both in phosphate buffer saline and largemouth bass serum.
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87.80.-y Biophysical techniques (research methods)
87.15.km Protein-protein interactions
87.14.E- Proteins
85.30.Tv Field effect devices

Diffusive reflectance for the free-space light propagation theory

Yuanzheng Si, Heng Mao, Bin Zhang, and Ming Jiang

Appl. Phys. Lett. 96, 013702 (2010); http://dx.doi.org/10.1063/1.3284520 (3 pages)

Online Publication Date: 7 January 2010

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Based on the free-space light propagation theory, the noncontact measurement technique for optical tomography provides high quality data sets by using charge coupled device camera for light detection. The free-space theory was originally formulated for a single object but did not take into account the reflection among object surfaces. However, complex geometries of small animals can induce multiple light reflections on surfaces. A major issue is how to model the surface reflectance to work with the free-space light propagation theory. In this letter, we utilize the Monte Carlo simulation technique to evaluate the performance of the free-space theory with multiple light reflections. Two types of surface reflectance have been simulated, including the specular or diffuse reflectance, respectively. It is found that for tissuelike objects the diffusive reflectance works the best with the free-space theory and a discrepancy occurs when the surface exhibits specular reflectance.
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42.25.Bs Wave propagation, transmission and absorption
02.70.Uu Applications of Monte Carlo methods
42.25.Gy Edge and boundary effects; reflection and refraction
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