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Applied Physics Letters / Volume 97 / Issue 13 / BIOPHYSICS AND BIO-INSPIRED SYSTEMS

Appl. Phys. Lett. 97, 133702 (2010); http://dx.doi.org/10.1063/1.3493659 (3 pages)

High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe

Xiang Li1, Jiechen Yin2, Changhong Hu1, Qifa Zhou1, K. Kirk Shung1, and Zhongping Chen2,3

1Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, University of Southern California, Los Angeles, California 90089, USA
2Department of Biomedical Engineering, University of California, Irvine, California 92697, USA
3Beckman Laser Institute, University of California, Irvine, California 92612, USA and Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, California 92697, USA

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(Received 5 May 2010; accepted 7 September 2010; published online 27 September 2010)

We report an integrated ultrasound (US) and optical coherence tomography (OCT) probe and system for intravascular imaging. The dual-function probe is based on a 50 MHz focused ring US transducer, with a centric hole for mounting OCT probe. The coaxial US and light beams are steered by a 45° mirror to enable coregistered US/OCT imaging simultaneously. Lateral resolution of US is improved due to focused ultrasonic beam. Mirror effects on US were investigated and in vitro imaging of a rabbit aorta has been carried out. The combined US-OCT system demonstrated high resolution in visualizing superficial arterial structures while retaining deep penetration of ultrasonic imaging.

© 2010 American Institute of Physics

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KEYWORDS and PACS

Keywords

biomedical ultrasonics, blood vessels, mirrors, optical tomography, ultrasonic imaging, ultrasonic transducers

PACS

  • 43.35.Wa

    Biological effects of ultrasound, ultrasonic tomography

  • 87.63.L-

    Visual imaging

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.3493659

PUBLICATION DATA

ISSN

0003-6951 (print)  
1077-3118 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

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