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24 Jan 2011

Volume 98, Issue 4, Articles (04xxxx)

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Appl. Phys. Lett. 98, 043101 (2011); http://dx.doi.org/10.1063/1.3536475 (3 pages)

Zhichao Ruan and Shanhui Fan
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Cold atmospheric pressure plasma jet interactions with plasmid DNA

D. O’Connell, L. J. Cox, W. B. Hyland, S. J. McMahon, S. Reuter, W. G. Graham, T. Gans, and F. J. Currell

Appl. Phys. Lett. 98, 043701 (2011); http://dx.doi.org/10.1063/1.3521502 (3 pages) | Cited 18 times

Online Publication Date: 25 January 2011

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The effect of a cold (<40 °C) radio frequency-driven atmospheric pressure plasma jet on plasmid DNA has been investigated. Gel electrophoresis was used to analyze the DNA forms post-treatment. The experimental data are fitted to a rate equation model that allows for quantitative determination of the rates of single and double strand break formation. The formation of double strand breaks correlates well with the atomic oxygen density. Taken with other measurements, this indicates that neutral components in the jet are effective in inducing double strand breaks.
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87.53.Ay Biophysical mechanisms of interaction
87.15.Tt Electrophoresis
87.14.gk DNA
52.20.-j Elementary processes in plasmas

Coupled vesicle morphogenesis and domain organization

Changjin Huang, Hongyan Yuan, and Sulin Zhang

Appl. Phys. Lett. 98, 043702 (2011); http://dx.doi.org/10.1063/1.3549176 (3 pages) | Cited 2 times

Online Publication Date: 26 January 2011

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Protein-enriched membrane domains with distinct biophysical properties have been thought as the basic organizing units of cellular membrane. Using particle dynamics simulations, here we study phase separation dynamics and domain formation in binary vesicles. Our simulations clearly show the intimate coupling between domain compositions, lateral domain organization, and vesicle shape transformation. Our simulation results provide insights into the essential role of membrane domains in the coordinated remodeling of cellular membranes and in protein and lipid sorting.
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87.16.D- Membranes, bilayers, and vesicles
87.14.ep Membrane proteins
87.14.E- Proteins
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