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12 Sep 2011

Volume 99, Issue 11, Articles (11xxxx)

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Appl. Phys. Lett. 99, 113501 (2011); http://dx.doi.org/10.1063/1.3634072 (3 pages)

Asif Islam Khan, Debanjan Bhowmik, Pu Yu, Sung Joo Kim, Xiaoqing Pan, Ramamoorthy Ramesh, and Sayeef Salahuddin
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Four-dimensional ultrasound current source density imaging of a dipole field

Z. H. Wang, R. Olafsson, P. Ingram, Q. Li, Y. Qin, and R. S. Witte

Appl. Phys. Lett. 99, 113701 (2011); http://dx.doi.org/10.1063/1.3632034 (3 pages) | Cited 1 time

Online Publication Date: 14 September 2011

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Ultrasound current source density imaging (UCSDI) potentially transforms conventional electrical mapping of excitable organs, such as the brain and heart. For this study, we demonstrate volume imaging of a time-varying current field by scanning a focused ultrasound beam and detecting the acoustoelectric (AE) interaction signal. A pair of electrodes produced an alternating current distribution in a special imaging chamber filled with a 0.9% NaCl solution. A pulsed 1 MHz ultrasound beam was scanned near the source and sink, while the AE signal was detected on remote recording electrodes, resulting in time-lapsed volume movies of the alternating current distribution.
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87.63.dh Ultrasonographic imaging
87.19.Hh Cardiac dynamics
87.19.L- Neuroscience

On the possible origin of bulk third harmonic generation in skin cells

Tung-Yu Su (蘇東榆), Chien-Sheng Liao (廖建盛), Chih-Yuan Yang (楊治原), Guan-Yu Zhuo (卓冠宇), Szu-Yu Chen (陳思妤), and Shi-Wei Chu (朱士維)

Appl. Phys. Lett. 99, 113702 (2011); http://dx.doi.org/10.1063/1.3638458 (3 pages)

Online Publication Date: 16 September 2011

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We studied third harmonic generation (THG) of melanin solution with concentrations similar to melanocytes in human skin. In contrast to conventional observation of THG at interface, bulk THG was detected inside the solution due to the formation of melanin hydrocolloids. A linear relationship between melanin concentration and THG intensity was found, suggesting THG originated from high-order hyper-Rayleigh scattering. By fitting this linear relationship, third-order hyperpolarizability of melanin hydrocolloids was determined to be three orders larger than that of water. Our result will be useful for interpretation of THG signals in skin and other tissues containing colloidal particles.
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87.63.L- Visual imaging
42.65.Ky Frequency conversion; harmonic generation, including higher-order harmonic generation
82.70.Dd Colloids
87.17.-d Cell processes
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