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Applied Physics Letters / Volume 99 / Issue 25 / NANOSCALE SCIENCE AND DESIGN

Appl. Phys. Lett. 99, 253106 (2011); http://dx.doi.org/10.1063/1.3671397 (3 pages)

DNA hybridization detection in a miniaturized electromagnetic band gap resonator

Mircea Dragoman1, Alina Cismaru1, Antonio Radoi1, Marius Voicu1, and Daniela Dragoman2

1National Institute for Research and Development in Microtechnology (IMT), P.O. Box 38-160, 023573 Bucharest, Romania
2Physics Department, University of Bucharest, P.O. Box MG-11, 077125 Bucharest, Romania

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(Received 8 October 2011; accepted 30 November 2011; published online 21 December 2011)

The hybridization of the deoxyribonucleic acid (DNA) is sensed in a miniaturized electromagnetic band gap resonator, which has a resonance frequency f0 = 17.3 GHz when unloaded. The resonance frequency f0 is shifted to the left when a single-stranded DNA is immobilized on the resonator and to the right for an immobilized double-stranded DNA. The shifted frequencies of the two states of the DNA are separated by a span of 1 GHz in the band 16-20 GHz and are explained by different effective electrical permittivity values of single- and double-stranded DNA molecules.

© 2011 American Institute of Physics

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KEYWORDS and PACS

Keywords

bioelectric phenomena, biomagnetism, DNA, microwave resonators, molecular biophysics, photonic band gap

PACS

ARTICLE DATA

Digital Object Identifier
http://dx.doi.org/10.1063/1.3671397

PUBLICATION DATA

ISSN

0003-6951 (print)  
1077-3118 (online)

Publisher

$abstract.society.value is a Member of CrossRef American Institute of Physics

For access to fully linked references, you need to log in.
    H.-L. Lee, H.-S. Lee, K.-H. Yoo, and J.-G. Yook, J. Appl. Phys. 108, 014908 (2010)JAPIAU000108000001014908000001.


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