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Appl. Phys. Lett. 99, 044101 (2011); http://dx.doi.org/10.1063/1.3608115 (3 pages)

Inertial focusing of non-spherical microparticles

Soojung Claire Hur1,2, Sung-Eun Choi3,4, Sunghoon Kwon3, and Dino Di Carlo2,5

1Mechanical and Aerospace Engineering Department, University of California Los Angeles, Los Angeles, California 90095, USA
2California NanoSystems Institute, Los Angeles, California 90095, USA
3Department of Electrical Engineering, Seoul National University, Seoul 151-742, South Korea
4Inter-university Semiconductor Research Center, Seoul National University Seoul, 151-742, South Korea
5Department of Bioengineering, University of California Los Angeles, Los Angeles, California 90095, USA

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(Received 18 May 2011; accepted 10 June 2011; published online 29 July 2011)

We have investigated the focusing and dynamics of non-spherical polymeric particles in microfluidic flows at finite Reynolds number. The rotational diameter, Dmax, of a particle, regardless of its cross-sectional shape, was found to determine the final focused position, except for the case of asymmetric disks. Additionally, elongated particles with larger Dmax exhibited longer residence times in a horizontal orientation than those with smaller Dmax. These findings inform approaches to hydrodynamically control shaped and barcoded particles for multiplexed biochemical assays.

© 2011 American Institute of Physics

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0003-6951 (print)  
1077-3118 (online)

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